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Affiliation of miR-125b, miR-17 and let-7c Dysregulations With Response to Anti-epidermal Progress Issue Receptor Monoclonal Antibodies in Sufferers With Metastatic Colorectal
Prevalence and traits of myeloproliferative neoplasms with concomitant monoclonal gammopathy
Of BCR-ABL adverse myeloproliferative neoplasm (MPN) sufferers, 3-14 % show a concomitant monoclonal gammopathy (MGUS). Nonetheless, literature on co-occurring MPN and MGUS is scarce, the molecular underpinnings are unknown and it’s unclear whether or not sufferers require a particular administration.
Right here, we in contrast the scientific and genetic options of MPN sufferers with and with out concomitant MGUS. Of 114 MPN sufferers prospectively studied by serum immunofixation (median age, 67 years; 36.0 % important thrombocythemia [ET], 24.6 % polycythemia vera [PV], 11.4 % secondary myelofibrosis [sMF], 28.1 % main myelofibrois [PMF]; 73.7 % JAK2 V617F constructive), 10 (9 %) harbored an M-protein.
No related scientific variations existed between MPN sufferers with or with out M-protein. Seven further MPN/MGUS sufferers had been retrospectively recognized in our MPN registry, yielding a complete of 17 sufferers (7 ET, Three PV, Three sMF, Four PMF). One affected person developed a number of myeloma (MM) and one smoldering MM. Seven of 12 sufferers analyzed carried mutations (e.g. in ASXL1 or TET2) along with these in JAK2 or CALR, and Four of 10 sufferers confirmed aberrant cytogenetics.
M-protein was primarily IgG (12/17), adopted by IgM (4/17). Within the two sufferers that underwent allogeneic stem cell transplantation mutant JAK2 and M-protein had been not detectable post-transplant. In conclusion, MGUS prevalence in our cohort was within the vary of earlier studies and at most barely larger than anticipated within the basic inhabitants.
MGUS presence didn’t correlate with a particular MPN entity, scientific options or genetic alterations. Our observations counsel that there isn’t any sturdy scientific or organic relationship between the incidence of MGUS and MPN.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L.
Description: A Monoclonal antibody against Human CST3 (monoclonal). The antibodies are raised in Mouse and are from clone 1H4. This antibody is applicable in WB
Description: A Monoclonal antibody against Human T. The antibodies are raised in Mouse and are from clone 394CT14.1.4. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human FYN. The antibodies are raised in Mouse and are from clone 1302CT390.118.237. This antibody is applicable in WB, FC, IHC-P, E
Monoclonal JUN antibody , Clone: 1306CT545.208.117
Description: A Monoclonal antibody against Human JUN . The antibodies are raised in Mouse and are from clone 1306CT545.208.117. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human VCP. The antibodies are raised in Mouse and are from clone 1344CT150.163.114. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human PHB. The antibodies are raised in Mouse and are from clone 1215CT487.109.106. This antibody is applicable in WB and IHC-P, E
Description: A Monoclonal antibody against Human SP1. The antibodies are raised in Mouse and are from clone 1326CT463.109.176. This antibody is applicable in WB, FC, IF, E
Description: A Monoclonal antibody against Human CD74. The antibodies are raised in Mouse and are from clone 1267CT820.116.140.154. This antibody is applicable in WB, FC, E
Description: A Monoclonal antibody against Human USP5. The antibodies are raised in Mouse and are from clone 1340CT704.170.140. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human RAC1. The antibodies are raised in Mouse and are from clone 1301CT276.121.104. This antibody is applicable in WB, FC, IHC-P, E
Description: A Monoclonal antibody against Human WNT4. The antibodies are raised in Mouse and are from clone 1698CT540.169.185. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human ATG5. The antibodies are raised in Mouse and are from clone 1358CT289.125.123. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human CDK5. The antibodies are raised in Mouse and are from clone 1321CT281.130.129. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human CDK5. The antibodies are raised in Mouse and are from clone 1321CT281.130.129. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human FLNA. The antibodies are raised in Mouse and are from clone 1273CT424.104.153. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human SRC. The antibodies are raised in Mouse and are from clone 1602CT774.225.92. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human CD138. The antibodies are raised in Mouse and are from clone 531CT15.4.1;531CT15.1.4. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human CREB1. The antibodies are raised in Mouse and are from clone 1335CT115.203.189. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human NFKB1. The antibodies are raised in Mouse and are from clone 1298CT792.105.117.133. This antibody is applicable in WB, FC, IHC-P, E
Description: A Monoclonal antibody against Human USP25. The antibodies are raised in Mouse and are from clone 1277CT376.106.171. This antibody is applicable in WB, E
Monoclonal AURKA Antibody, Clone: 1364CT291.108.155
Description: A Monoclonal antibody against Human AURKA . The antibodies are raised in Mouse and are from clone 1364CT291.108.155. This antibody is applicable in WB and IHC-P, E
Description: A Monoclonal antibody against Human APEX1. The antibodies are raised in Mouse and are from clone 1518CT337.123.86.269.232. This antibody is applicable in IF, IHC-P, WB, E
Description: A Monoclonal antibody against Human Stat3. The antibodies are raised in Mouse and are from clone 1200CT146.104.153. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human STAT3. The antibodies are raised in Mouse and are from clone 1200CT146.104.153. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human EPHA6. The antibodies are raised in Mouse and are from clone 1426CT591.205.91.119. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human PPARA. The antibodies are raised in Mouse and are from clone 1331CT894.186.143. This antibody is applicable in WB, FC, IF, IHC-P, E
Description: A Monoclonal antibody against Human CRYAB. The antibodies are raised in Mouse and are from clone 1329CT523.140.120. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human YWHAZ. The antibodies are raised in Mouse and are from clone 1314CT423.108.153.173.140. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human CDK4. The antibodies are raised in Mouse and are from clone 1529CT850.162.73. This antibody is applicable in IHC-P, WB, E
Description: A Monoclonal antibody against Human VAV1. The antibodies are raised in Mouse and are from clone 1582CT802.383.58. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human MITF. The antibodies are raised in Mouse and are from clone 1607CT834.207.47. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human SUFU. The antibodies are raised in Mouse and are from clone 1783CT536.263.29. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human GLS2. The antibodies are raised in Mouse and are from clone 1758CT879.217.60. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human AKT2. The antibodies are raised in Mouse and are from clone 1623CT791.157.67.66. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human CDK5. The antibodies are raised in Mouse and are from clone 1552CT262.105.8. This antibody is applicable in IF, FC, IHC-P, WB, E
Description: A Monoclonal antibody against Human Musk. The antibodies are raised in Mouse and are from clone 1429CT456.173.44. This antibody is applicable in WB and IHC-P, E
Anti Beta-Estradiol Monoclonal Antibody (1977CT128.130.83)
Affiliation of miR-125b, miR-17 and let-7c Dysregulations With Response to Anti-epidermal Progress Issue Receptor Monoclonal Antibodies in Sufferers With Metastatic Colorectal Most cancers
Background/purpose: MicroRNAs (miRs) play an essential function within the regulation of cancer-related processes and are promising candidates for most cancers biomarkers. The purpose of the examine was to guage the affiliation of response to anti-EGFR monoclonal antibodies (mAbs) with chosen miR expression profiles, together with miR-125b, let-7c, miR-99a, miR-17, miR-143 and miR-145 in metastatic colorectal most cancers (mCRC) sufferers.
Sufferers and strategies: This retrospective examine included 46 sufferers with mCRC harbouring wild-type RAS gene handled with cetuximab or panitumumab mixed with chemotherapy in first- or second-line remedy. The miR expression was assessed utilizing qRT-PCR.
Outcomes: Down-regulation of miR-125b and let-7c and up-regulation of miR-17 had been discovered within the tumour tissue (p=0.0226, p=0.0040, p<0.0001). Goal response fee (ORR) was related to up-regulation of miR-125b (p=0.0005). Illness management fee (DCR) was related with up-regulation of miR-125b and let-7c (p=0.0383 and p=0.0255) and down-regulation of miR-17 (p=0.0464). MiR-125b confirmed correlation with progression-free and general survival (p=0.055 and p=0.006).
Conclusion: The outcomes present that up-regulation of miR-125b is related with larger ORR and DCR and longer survival; let-7c up-regulation and miR-17 down-regulation are related to larger DCR in mCRC sufferers handled with anti-EGFR mAbs.
Engineering Staphylococcal Protein A for high-throughput affinity purification of monoclonal antibodies
Protein A chromatography is without doubt one of the most generally used purification steps within the manufacturing of the assorted courses of recombinant and non-recombinant antibodies. As a result of larger price, decrease binding capability, and restricted life cycle of Protein A ligand, this affinity-based purification step is usually one of the important contributors to the price of manufacturing of monoclonal antibody (mAb) merchandise.
Within the final decade, there was important progress in enhancing the Protein A chromatography throughput by designing new engineered Staphylococcal Protein A (SPA) variants with larger dynamic binding capability, appreciable alkaline tolerance, and gentle acidic elution pH. This assessment goals at summarizing the assorted protein engineering approaches used for enhancing the throughput of the Protein A-based affinity purification of varied immunoglobulins.
With biopharmaceutical producers working below ever-increasing strain in the direction of decreasing the price of manufacturing, these advances in engineered protein A variants will assist in processing bigger cell tradition volumes with excessive throughput and thereby considerably decrease the price of uncooked supplies.
Description: A monoclonal antibody for detection of Acetyl P53 K382) from Human, Mouse, Rat. This Acetyl P53 K382) antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Acetyl P53 (K382)
Description: A monoclonal antibody for detection of Acetyl P53 K382) from Human, Mouse, Rat. This Acetyl P53 K382) antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Acetyl P53 (K382)
Description: A monoclonal antibody for detection of Acetyl P53 K382) from Human, Mouse, Rat. This Acetyl P53 K382) antibody is for IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide of Acetyl P53 (K382)
Description: A Monoclonal antibody against Human TUBA2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F10-2F2. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human CRX (monoclonal) (M03). The antibodies are raised in mouse and are from clone 2F12. This antibody is applicable in WB, E
Monoclonal SMO Antibody (monoclonal) (M10), Clone: 2F12
Description: A Monoclonal antibody against Human SMO (monoclonal) (M10). The antibodies are raised in mouse and are from clone 2F12. This antibody is applicable in E
Description: A Monoclonal antibody against Human CTSD (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F12-1B9. This antibody is applicable in WB and IHC, IP, E
Description: A Monoclonal antibody against Human CDC45L (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 3F11-1F3. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human YAP1 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 2F12. This antibody is applicable in WB, IHC and IF
Description: A Monoclonal antibody against Human PPOX (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F10. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human PFN2 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 5F11. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human SALF (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5F12. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human CDK4 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 4F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human CLK3 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 1F10. This antibody is applicable in WB, IHC and IF
Description: A Monoclonal antibody against Human HEY1 (monoclonal) (M09). The antibodies are raised in mouse and are from clone 1F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human IL27 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F12. This antibody is applicable in WB, IP
Description: A Monoclonal antibody against Human JAK3 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 3F10. This antibody is applicable in E
Description: A Monoclonal antibody against Human KLK8 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human AKT1 (monoclonal) (M09). The antibodies are raised in mouse and are from clone 6F11. This antibody is applicable in WB and IF
Description: A Monoclonal antibody against Human CES2 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 4F12. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human IDH2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5F11. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human HIP1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F12. This antibody is applicable in WB and IHC, IP, E
Description: A Monoclonal antibody against Human SOX9 (monoclonal) (M04). The antibodies are raised in Mouse and are from clone 3F11. This antibody is applicable in WB, IHC and IF
Description: A Monoclonal antibody against Human NXT1 (monoclonal) (M08). The antibodies are raised in mouse and are from clone 4F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human CDSN (monoclonal) (M01). The antibodies are raised in mouse and are from clone 6F11. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human GDF7 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 4F10. This antibody is applicable in E
Description: A Monoclonal antibody against Human PSME2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F11-1A3. This antibody is applicable in WB and IF
Description: A Monoclonal antibody against Human PCBP2 (monoclonal) (M07). The antibodies are raised in mouse and are from clone 5F12. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human EFNA5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F12. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human POLA2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human PRKCA (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human RAB3B (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F12. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human RASA3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F11. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human SNAI2 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human TBX21 (monoclonal) (M10). The antibodies are raised in mouse and are from clone 2F10. This antibody is applicable in WB
Description: A Monoclonal antibody against Human TFDP3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human TFDP3 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 3F11. This antibody is applicable in WB
Description: A Monoclonal antibody against Human TNNT3 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 1F12. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human WDR79 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 1F12. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human FGF21 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human GSTA3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F11. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human PDCL3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F10. This antibody is applicable in WB
Description: A Monoclonal antibody against Human TSSK1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4F12. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human WDR77 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F10. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human PRTN3 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 2F10. This antibody is applicable in E
Description: A Monoclonal antibody against Human STK33 (monoclonal) (M07). The antibodies are raised in mouse and are from clone 3F10. This antibody is applicable in WB, IHC and IF
Description: A Monoclonal antibody against Human STK33 (monoclonal) (M09). The antibodies are raised in mouse and are from clone 1F10. This antibody is applicable in WB and IF, IP
Description: A Monoclonal antibody against Human PYCRL (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4F11. This antibody is applicable in WB and IF, IP, E
Description: A Monoclonal antibody against Human DEAF1 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 3F11. This antibody is applicable in WB
Description: A Monoclonal antibody against Human FBXO6 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F10. This antibody is applicable in WB, IP
Description: A Monoclonal antibody against Human GATA2 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 2F12. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human NDST1 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB
Description: A Monoclonal antibody against Human NSEP1 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 4F12. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human NUP62 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F12. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human NR0B1 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 1F10. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human NTNG2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4F11. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human CCL14 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F12. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human CFLAR (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F12. This antibody is applicable in WB, IHC and IF
Description: A Monoclonal antibody against Human HNF4A (monoclonal) (M05). The antibodies are raised in mouse and are from clone 1F12. This antibody is applicable in WB and IF
Description: A Monoclonal antibody against Human HTRA2 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 4F10. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human MTHFR (monoclonal) (M06). The antibodies are raised in mouse and are from clone 1F10. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human HOXD8 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 10F8. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human ITGB2 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 5F12. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human MKNK1 (monoclonal) (M14). The antibodies are raised in mouse and are from clone 2F12. This antibody is applicable in WB, IHC and IF
Description: A Monoclonal antibody against Human MKNK2 (monoclonal) (M04). The antibodies are raised in mouse and are from clone 4F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human MYBPH (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F11. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human NCOA4 (monoclonal) (M05). The antibodies are raised in mouse and are from clone 1F11. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human MAP3K4 (monoclonal) (M08). The antibodies are raised in mouse and are from clone 4F10. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human CXCL12 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 1F10. This antibody is applicable in E
Description: A Monoclonal antibody against Human RNF126 (monoclonal) (M04). The antibodies are raised in Mouse and are from clone 3F11. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human TRIM25 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 5F12. This antibody is applicable in WB and IF
Description: A Monoclonal antibody against Human FOXO1A (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 1F11. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human CALML5 (monoclonal) (M16). The antibodies are raised in Mouse and are from clone 2F10. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human CDC14A (monoclonal) (M02). The antibodies are raised in mouse and are from clone 1F11. This antibody is applicable in WB and IF
Description: A Monoclonal antibody against Human FAM50A (monoclonal) (M02). The antibodies are raised in mouse and are from clone 5F10. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human FBXO42 (monoclonal) (M02). The antibodies are raised in mouse and are from clone 2F10. This antibody is applicable in WB
Description: A Monoclonal antibody against Human TIMM8A (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB and IHC, E
Description: A Monoclonal antibody against Human GSDMDC1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F12-1B2. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human ORM1 (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 2F9-1F10. This antibody is applicable in WB and IHC, IP, E
Description: A Monoclonal antibody against Human FASN (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 3F2-1F3. This antibody is applicable in WB, IHC and IF, IP
Description: A Monoclonal antibody against Human CEACAM1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F10. This antibody is applicable in E
Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Description: A Monoclonal antibody against Human FLJ20105 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F12-2B10. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human TNFRSF17 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F10. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human PNLIPRP2 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 4F10. This antibody is applicable in E
Description: A Monoclonal antibody against Human ADAMTS13 (monoclonal) (M06). The antibodies are raised in Mouse and are from clone 4F12. This antibody is applicable in E
Description: A Monoclonal antibody against Human FLJ23356 (monoclonal) (M03). The antibodies are raised in mouse and are from clone 6F10. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human B2M (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F9-2C2. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human DSU (monoclonal) (M01). The antibodies are raised in mouse and are from clone 8F9-1B2. This antibody is applicable in WB, IP, E
Description: A Monoclonal antibody against Human PHB (monoclonal) (M01). The antibodies are raised in mouse and are from clone 3F4-2B2. This antibody is applicable in WB, IHC and IF, E
Description: A Monoclonal antibody against Human PPIA (monoclonal) (M01). The antibodies are raised in Mouse and are from clone 1F4-1B5. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human FRS2 (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 1F7-1D6. This antibody is applicable in WB
Description: A Monoclonal antibody against Human FABP3 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 4F6-1D6. This antibody is applicable in WB, E
Description: A Monoclonal antibody against Human ANXA5 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F4-1A5. This antibody is applicable in WB, IHC and IF, IP
Description: A Monoclonal antibody against Human CCNL1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 1F7-1C5. This antibody is applicable in WB and IF, E
Description: A Monoclonal antibody against Human DNPEP (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F9-3A7. This antibody is applicable in WB and IF
