Backside-up pattern preparation for the LC-MS/MS quantification of anti-cancer monoclonal antibodies in bio matrices
Therapeutic monoclonal antibodies (mAbs) are quickly taking up the therapy of many malignancies, and an astonishing variety of mAbs is in improvement. This causes a excessive demand for quantification of mAbs in biomatrices each for measuring therapeutic mAb concentrations and to assist pharmacokinetics and pharmacodynamics research.
Conventionally, ligand-binding assays are used for these functions, however LC-MS is gaining recognition. Though intact (top-down) and subunit (middle-down) mAb quantification is reported, signature peptide (bottom-up) quantification is at the moment most advantageous.
This overview gives an outline of the reported bottom-up mAb quantification strategies in biomatrices in addition to basic suggestions concerning signature peptide and inner normal choice, reagent use and optimization of digestion in bottom-up quantification strategies.
Pepsin (PP) Monoclonal Antibody (Human) |
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4-MAA632Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP) |
Pepsin (PP) Monoclonal Antibody (Human), PE |
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4-MAA632Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with PE. |
Pepsin (PP) Monoclonal Antibody (Human), APC |
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4-MAA632Hu22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with APC. |
Pepsin (PP) Monoclonal Antibody (Human), Cy3 |
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4-MAA632Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with Cy3. |
Pepsin (PP) Monoclonal Antibody (Human), HRP |
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4-MAA632Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with HRP. |
Pepsin (PP) Monoclonal Antibody (Human), FITC |
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4-MAA632Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with FITC. |
Pepsin (PP) Monoclonal Antibody (Human), Biotinylated |
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4-MAA632Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with Biotin. |
PE-Linked Monoclonal Antibody to Pepsin (PP) |
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MBS2107564-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Pepsin (PP) Monoclonal Antibody (Human), APC-Cy7 |
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4-MAA632Hu22-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsin (PP). This antibody is labeled with APC-Cy7. |
APC-Linked Monoclonal Antibody to Pepsin (PP) |
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MBS2107565-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Cy3-Linked Monoclonal Antibody to Pepsin (PP) |
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MBS2107566-INQUIRE | MyBiosource | INQUIRE | Ask for price |
HRP-Linked Monoclonal Antibody to Pepsin (PP) |
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MBS2107569-INQUIRE | MyBiosource | INQUIRE | Ask for price |
FITC-Linked Monoclonal Antibody to Pepsin (PP) |
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MBS2107568-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Botin-Linked Monoclonal Antibody to Pepsin (PP) |
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MBS2107567-INQUIRE | MyBiosource | INQUIRE | Ask for price |
APC/Cy7 Linked Monoclonal Antibody to Pepsin (PP) |
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MBS2107563-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Anti Pepsinogen II/PGC mouse monoclonal antibody |
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MBS157803-01mg | MyBiosource | 0.1mg | EUR 350 |
Anti Pepsinogen II/PGC mouse monoclonal antibody |
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MBS157803-5x01mg | MyBiosource | 5x0.1mg | EUR 1250 |
Mouse anti Human Pepsinogen C/PGC Monoclonal Antibody |
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MBS2543681-006mL | MyBiosource | 0.06mL | EUR 335 |
Mouse anti Human Pepsinogen C/PGC Monoclonal Antibody |
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MBS2543681-012mL | MyBiosource | 0.12mL | EUR 520 |
Mouse anti Human Pepsinogen C/PGC Monoclonal Antibody |
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MBS2543681-02mL | MyBiosource | 0.2mL | EUR 800 |
Mouse anti Human PGA4/Pepsinogen A Monoclonal Antibody |
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MBS2543728-006mL | MyBiosource | 0.06mL | EUR 250 |
Mouse anti Human PGA4/Pepsinogen A Monoclonal Antibody |
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MBS2543728-012mL | MyBiosource | 0.12mL | EUR 370 |
Mouse anti Human PGA4/Pepsinogen A Monoclonal Antibody |
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MBS2543728-02mL | MyBiosource | 0.2mL | EUR 550 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone:1H5] |
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E45M18806 | EnoGene | 100 ug | EUR 595 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone 1H5] |
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E45M18806V-2 | EnoGene | 50 ul | EUR 195 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone:3C2] |
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E45M19074 | EnoGene | 100 ug | EUR 595 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone 3C2] |
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E45M19074V-2 | EnoGene | 50 ul | EUR 195 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone:4F6] |
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E45M19119 | EnoGene | 100 ug | EUR 595 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone 4F6] |
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E45M19119V-2 | EnoGene | 50 ul | EUR 195 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone:5C9] |
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E45M19120 | EnoGene | 100 ug | EUR 595 |
Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone 5C9] |
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E45M19120V-2 | EnoGene | 50 ul | EUR 195 |
Pepsinogen A mouse monoclonal antibody, clone 8003 (99/12), Purified |
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BM676 | Origene Technologies GmbH | 200 µg | Ask for price |
Pepsinogen II (PGC) mouse monoclonal antibody, clone 90/11, Ig Fraction |
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BM678 | Origene Technologies GmbH | 200 µg | Ask for price |
Pepsinogen II (PGC) mouse monoclonal antibody, clone L10CC10, Ig Fraction |
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AM32098PU-N | Origene Technologies GmbH | 100 µg | Ask for price |
Monoclonal Antibody to Pepsinogen I |
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MBS318870-1mg | MyBiosource | 1mg | EUR 930 |
Monoclonal Antibody to Pepsinogen I |
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MBS318870-5x1mg | MyBiosource | 5x1mg | EUR 4010 |
Monoclonal Antibody to Pepsinogen II |
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MBS318871-1mg | MyBiosource | 1mg | EUR 930 |
Monoclonal Antibody to Pepsinogen II |
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MBS318871-5x1mg | MyBiosource | 5x1mg | EUR 4010 |
Monoclonal Antibody to Pepsinogen II |
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MBS318872-1mg | MyBiosource | 1mg | EUR 930 |
Monoclonal Antibody to Pepsinogen II |
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MBS318872-5x1mg | MyBiosource | 5x1mg | EUR 4010 |
Monoclonal Antibody to Pepsinogen I |
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MBS318873-1mg | MyBiosource | 1mg | EUR 930 |
Monoclonal Antibody to Pepsinogen I |
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MBS318873-5x1mg | MyBiosource | 5x1mg | EUR 4010 |
Monoclonal Antibody to Pepsinogen I |
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MBS318874-1mg | MyBiosource | 1mg | EUR 930 |
Monoclonal Antibody to Pepsinogen I |
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MBS318874-5x1mg | MyBiosource | 5x1mg | EUR 4010 |
Pepsinogen A (PGA) Monoclonal Antibody |
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CAU29207-100ul | Biomatik Corporation | 100ul | EUR 242.9 |
Pepsinogen A (PGA) Monoclonal Antibody |
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CAU29207-200ul | Biomatik Corporation | 200ul | EUR 304.1 |
Pepsinogen C (PGC) Monoclonal Antibody |
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CAU29208-100ul | Biomatik Corporation | 100ul | EUR 225.6 |
Pepsinogen C (PGC) Monoclonal Antibody |
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CAU29208-200ul | Biomatik Corporation | 200ul | EUR 282.2 |
Pepsinogen C (PGC) Monoclonal Antibody |
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CAU29209-100ul | Biomatik Corporation | 100ul | EUR 242.9 |
Pepsinogen C (PGC) Monoclonal Antibody |
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CAU29209-200ul | Biomatik Corporation | 200ul | EUR 304.1 |
Pepsinogen A (PGA) Monoclonal Antibody |
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CAU29499-100ul | Biomatik Corporation | 100ul | EUR 242.9 |
Pepsinogen A (PGA) Monoclonal Antibody |
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CAU29499-200ul | Biomatik Corporation | 200ul | EUR 304.1 |
Pepsinogen A (PGA) Monoclonal Antibody |
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CAU29757-100ul | Biomatik Corporation | 100ul | EUR 225.6 |
Pepsinogen A (PGA) Monoclonal Antibody |
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CAU29757-200ul | Biomatik Corporation | 200ul | EUR 282.2 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu21 | Cloud-Clone | 100ul | EUR 253 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu22 | Cloud-Clone | 100ul | EUR 235 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu23 | Cloud-Clone | 100ul | EUR 252 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu24 | Cloud-Clone | 100ul | EUR 243 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu25 | Cloud-Clone | 100ul | EUR 243 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu26 | Cloud-Clone | 100ul | EUR 239 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu27 | Cloud-Clone | 100ul | EUR 243 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu28 | Cloud-Clone | 100ul | EUR 239 |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MAA165Hu29 | Cloud-Clone | 100ul | EUR 243 |
Monoclonal Antibody to Pepsinogen C (PGC) |
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MAA166Hu22 | Cloud-Clone | 100ul | EUR 235 |
Monoclonal Antibody to Pepsinogen C (PGC) |
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MAA166Ra22 | Cloud-Clone | 100ul | EUR 253 |
Monoclonal Antibody to Pepsinogen C (PGC) |
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MBS2012649-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen C (PGC) |
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MBS2025678-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MBS2025737-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MBS2090660-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MBS2085826-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MBS2138440-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MBS2138441-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MBS2138442-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Monoclonal Antibody to Pepsinogen A (PGA) |
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MBS2138443-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Pepsinogen A (PGA) Monoclonal Antibody (Pig) |
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4-MAA165Hu21 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Pepsinogen A (PGA) |
Pepsinogen A (PGA) Monoclonal Antibody (Rat) |
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4-MAA165Ra21 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen A (PGA) |
Pepsinogen C (PGC) Monoclonal Antibody (Rat) |
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4-MAA166Ra22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen C (PGC) |
Pepsin (PP) Antibody |
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20-abx100019 | Abbexa |
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Pepsin (PP) Antibody |
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20-abx100020 | Abbexa |
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Pepsin (PP) Antibody |
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20-abx132317 | Abbexa |
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Pepsin (PP) Antibody |
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20-abx177932 | Abbexa |
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Pepsin (PP) Antibody |
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20-abx177933 | Abbexa |
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Pepsin (PP) Antibody |
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20-abx177934 | Abbexa |
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Pepsinogen A (PGA) Monoclonal Antibody (Human) |
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4-MAA165Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsinogen A (PGA) |
Pepsinogen C (PGC) Monoclonal Antibody (Human) |
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4-MAA166Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsinogen C (PGC) |
Pepsinogen A (PGA) Monoclonal Antibody (Pig), PE |
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4-MAA165Hu21-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Pepsinogen A (PGA). This antibody is labeled with PE. |
Pepsinogen A (PGA) Monoclonal Antibody (Rat), PE |
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4-MAA165Ra21-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen A (PGA). This antibody is labeled with PE. |
Pepsinogen C (PGC) Monoclonal Antibody (Rat), PE |
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4-MAA166Ra22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen C (PGC). This antibody is labeled with PE. |
Pepsinogen A (PGA) Monoclonal Antibody (Pig), APC |
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4-MAA165Hu21-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Pepsinogen A (PGA). This antibody is labeled with APC. |
Pepsinogen A (PGA) Monoclonal Antibody (Pig), Cy3 |
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4-MAA165Hu21-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Pepsinogen A (PGA). This antibody is labeled with Cy3. |
Pepsinogen A (PGA) Monoclonal Antibody (Pig), HRP |
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4-MAA165Hu21-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Pepsinogen A (PGA). This antibody is labeled with HRP. |
Pepsinogen A (PGA) Monoclonal Antibody (Rat), APC |
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4-MAA165Ra21-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen A (PGA). This antibody is labeled with APC. |
Pepsinogen A (PGA) Monoclonal Antibody (Rat), Cy3 |
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4-MAA165Ra21-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen A (PGA). This antibody is labeled with Cy3. |
Pepsinogen A (PGA) Monoclonal Antibody (Rat), HRP |
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4-MAA165Ra21-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen A (PGA). This antibody is labeled with HRP. |
Pepsinogen C (PGC) Monoclonal Antibody (Rat), APC |
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4-MAA166Ra22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen C (PGC). This antibody is labeled with APC. |
Pepsinogen C (PGC) Monoclonal Antibody (Rat), Cy3 |
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4-MAA166Ra22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen C (PGC). This antibody is labeled with Cy3. |
Pepsinogen C (PGC) Monoclonal Antibody (Rat), HRP |
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4-MAA166Ra22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen C (PGC). This antibody is labeled with HRP. |
Pepsinogen A (PGA) Monoclonal Antibody (Pig), FITC |
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4-MAA165Hu21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Pepsinogen A (PGA). This antibody is labeled with FITC. |
Pepsinogen A (PGA) Monoclonal Antibody (Human), PE |
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4-MAA165Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Pepsinogen A (PGA). This antibody is labeled with PE. |
Pepsinogen A (PGA) Monoclonal Antibody (Rat), FITC |
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4-MAA165Ra21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Pepsinogen A (PGA). This antibody is labeled with FITC. |
Formulating monoclonal antibodies as powders for reconstitution at excessive focus utilizing spray-drying: Trehalose/amino acid combos as reconstitution time lowering and stability bettering formulations
- To extend their stability, therapeutic (or monoclonal) antibodies (mAbs) are sometimes formulated as solids by utilizing quite a lot of drying strategies, e.g. freeze-drying, spray-drying, or spray freeze-drying. The addition of excipients is required to protect stability of the protein throughout the drying course of and subsequent storage of the ensuing stable type.
- The addition of low molecular weight excipients, reminiscent of amino acids, to sugar based mostly spray- and freeze-dried formulations has been urged to enhance the storage stability of proteins within the dried state.
- On this research sugars (sucrose, trehalose), amino acids (Gly, Ala, Professional, Ser, Val, Leu, Ile, Gln, His, Lys, Arg, Phe, Trp) and combos thereof have been investigated for his or her stabilizing impact throughout spray-drying and subsequent storage and for his or her reconstitution time lowering impact. Two IgG4 mAbs have been used as mannequin antibodies.
- From an preliminary screening research, primary and small impartial amino acids, together with a sugar, reminiscent of sucrose or trehalose, confirmed reconstitution time lowering and stabilizing properties. Arg specifically displayed glorious reconstitution and stability enhancing properties. Furthermore, Arg was the one amino acid offering stabilizing properties akin to sucrose or trehalose.
- Earlier work by the authors described a statistically substantiated comparability between the three primary amino acids in a sugar containing formulation, albeit restricted to a single focus stage [5]. Due to this fact, a follow-up design of experiments (DoE) research was carried out to find out the optimum trehalose/amino acid content material required for an optimum protein stability and reconstitution time and to check the results of two primary amino acids, Lys and Arg, to these of two impartial amino acids, Gly and Professional. The carried out DoE coated a variety of trehalose (30 – 120 mM) and amino acid (50 – 150 mM)
- The focus of trehalose was discovered to be the principle contributor to a discount in reconstitution time and a rise in stability. Right here we present that the addition of amino acids reminiscent of Gly, Professional, and Lys doesn’t enhance stability nor does it cut back the reconstitution time. Of the examined amino acids, solely Arg confirmed a marked discount in reconstitution time and enchancment in stability in comparison with a trehalose.
- Furthermore, the properties displayed by Arg may justify its utility as the principle stabilizer in spray-dried mAb formulations, eliminating the necessity for a sugar matrix altogether. However the weight ratio of stabilizer to protein was discovered the issue exerting the strongest total affect on the formulation’s reconstitution time and stability. Extra particularly, adequate bodily stability and a suitable reconstitution time may very well be obtained with a protein to stabilizer weight ratio of no less than 1:1.
Analysis of two level of care applied sciences for measuring monoclonal antibody therapeutic-A concentrations in blood
Intention: Present blood monitoring strategies require pattern assortment and testing at a central lab, which might take days. Level of care (POC) gadgets with fast turnaround time can present another with sooner outcomes, permitting for real-time information main to higher therapy selections for sufferers.
Outcomes/Methodology: An assay to measure monoclonal antibody therapeutic-A was developed on two POC gadgets. Information generated utilizing 75 serum samples (65 medical & ten spiked samples) present correlative outcomes to the information generated utilizing Gyrolab expertise.
Conclusion: This case research makes use of a monoclonal antibody therapeutic-A focus assay for instance to display the potential of POC applied sciences as a viable different to central lab testing with fast outcomes permitting for real-time decision-making.
PON1 Mouse Monoclonal Antibody [Clone:2A6] |
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E45M11046 | EnoGene | 100 ug | EUR 595 |
PON1 Mouse Monoclonal Antibody [Clone 2A6] |
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E45M11046V-2 | EnoGene | 50 ul | EUR 195 |
PON1 Mouse Monoclonal Antibody [Clone:1F7] |
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E45M11047 | EnoGene | 100 ug | EUR 595 |
PON1 Mouse Monoclonal Antibody [Clone 1F7] |
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E45M11047V-2 | EnoGene | 50 ul | EUR 195 |
PON1 mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) |
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TA502528 | Origene Technologies GmbH | 100 µl | Ask for price |
PON1 mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) |
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TA502528S | Origene Technologies GmbH | 30 µl | Ask for price |
PON1 mouse monoclonal antibody, clone OTI2A6 (formerly 2A6) |
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TA502610 | Origene Technologies GmbH | 100 µl | Ask for price |
PON1 mouse monoclonal antibody, clone OTI2A6 (formerly 2A6) |
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TA502610S | Origene Technologies GmbH | 30 µl | Ask for price |
PON1 mouse monoclonal antibody, clone OTI1F7 (formerly 1F7) |
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TA502611 | Origene Technologies GmbH | 100 µl | Ask for price |
PON1 mouse monoclonal antibody, clone OTI1F7 (formerly 1F7) |
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TA502611S | Origene Technologies GmbH | 30 µl | Ask for price |
PON1 mouse monoclonal antibody, clone OTI2A9 (formerly 2A9) |
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TA502612 | Origene Technologies GmbH | 100 µl | Ask for price |
PON1 mouse monoclonal antibody, clone OTI2A9 (formerly 2A9) |
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TA502612S | Origene Technologies GmbH | 30 µl | Ask for price |
Monoclonal PON1 Antibody, Clone: 4G8D3 |
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AMR09437G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A Monoclonal antibody against Human PON1. The antibodies are raised in Mouse and are from clone 4G8D3. This antibody is applicable in WB and IHC, FC, ICC, E |
Rabbit Anti Human PON1 Monoclonal Clone ACAG-16 |
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IRBAHUPON1ACAG16C100UL | Innovative research | each | EUR 496 |
Description: Rabbit Anti Human PON1 Monoclonal Clone ACAG-16 |
Monoclonal PON1 Antibody, Clone: 4G8A12 |
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AMM02955G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A Monoclonal antibody against Human PON1. The antibodies are raised in Mouse and are from clone 4G8A12. This antibody is applicable in WB and IHC, FC, E |
Monoclonal Antibody to Paraoxonase 1 (PON1) |
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MAA243Ra21 | Cloud-Clone | 100ul | EUR 253 |
PON1 Mouse Monoclonal Antibody |
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E10-30571 | EnoGene | 100 μl | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
PON1 Capture mouse monoclonal antibody, ELISA and Luminex validated, clone OTI1F7 |
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TA600112 | Origene Technologies GmbH | 100 µg | Ask for price |
PON1 Capture mouse monoclonal antibody, ELISA and Luminex validated, clone OTI2A6 |
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TA600113 | Origene Technologies GmbH | 100 µg | Ask for price |
PON1 Capture mouse monoclonal antibody, ELISA and Luminex validated, clone OTI2D4 |
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TA600114 | Origene Technologies GmbH | 100 µg | Ask for price |
Anti-PON1 Mouse Monoclonal Antibody [Clone ID: OTI1F7] |
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M00516-4 | BosterBio | 100ul | EUR 523 |
Description: Boster Bio PON1 mouse monoclonal antibody, clone OTI1F7 (formerly 1F7). Catalog# M00516-4. Tested in ELISA, FC, IHC, WB. This antibody reacts with Human. |
Anti-PON1 Mouse Monoclonal Antibody [Clone ID: OTI2D4] |
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M00516-5 | BosterBio | 100ul | EUR 523 |
Description: Boster Bio PON1 mouse monoclonal antibody, clone OTI2D4 (formerly 2D4). Catalog# M00516-5. Tested in ELISA, FC, IF, IHC, WB. This antibody reacts with Human. |
Mouse Monoclonal Antibody to PON1 |
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E10-30571A | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
Mouse Monoclonal Antibody to PON1 |
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E10-30572 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
Mouse Monoclonal Antibody to PON1 |
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sAP-0865 | Angio Proteomie | 50ug | EUR 270 |
Mouse Monoclonal Antibody to PON1 |
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sAP-0866 | Angio Proteomie | 50ug | EUR 270 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527855-01mL | MyBiosource | 0.1mL | EUR 305 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527855-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527855-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527855-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527855-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527856-01mL | MyBiosource | 0.1mL | EUR 305 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527856-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527856-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527856-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Mouse Monoclonal Antibody to PON1 |
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MBS8527856-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
Mouse Monoclonal PON1 Antibody (4G8D3) |
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TA336952 | Origene Technologies GmbH | 100 µl | Ask for price |
Carrier-free (BSA/glycerol-free) PON1 mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) |
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CF502528 | Origene Technologies GmbH | 100 µg | Ask for price |
Carrier-free (BSA/glycerol-free) PON1 mouse monoclonal antibody, clone OTI2A6 (formerly 2A6) |
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CF502610 | Origene Technologies GmbH | 100 µg | Ask for price |
Carrier-free (BSA/glycerol-free) PON1 mouse monoclonal antibody, clone OTI1F7 (formerly 1F7) |
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CF502611 | Origene Technologies GmbH | 100 µg | Ask for price |
Carrier-free (BSA/glycerol-free) PON1 mouse monoclonal antibody, clone OTI2A9 (formerly 2A9) |
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CF502612 | Origene Technologies GmbH | 100 µg | Ask for price |
PON3 Mouse Monoclonal Antibody [Clone:4H9] |
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E45M17755 | EnoGene | 100 ug | EUR 595 |
PON3 Mouse Monoclonal Antibody [Clone 4H9] |
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E45M17755V-2 | EnoGene | 50 ul | EUR 195 |
PON3 Mouse Monoclonal Antibody [Clone:5C3] |
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E45M17756 | EnoGene | 100 ug | EUR 595 |
PON3 Mouse Monoclonal Antibody [Clone 5C3] |
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E45M17756V-2 | EnoGene | 50 ul | EUR 195 |
PON3 Mouse Monoclonal Antibody [Clone:1A5] |
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E45M17757 | EnoGene | 100 ug | EUR 595 |
PON3 Mouse Monoclonal Antibody [Clone 1A5] |
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E45M17757V-2 | EnoGene | 50 ul | EUR 195 |
PON3 Mouse Monoclonal Antibody [Clone:5B5] |
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E45M17777 | EnoGene | 100 ug | EUR 595 |
PON3 Mouse Monoclonal Antibody [Clone 5B5] |
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E45M17777V-2 | EnoGene | 50 ul | EUR 195 |
PON3 Mouse Monoclonal Antibody [Clone:1F12] |
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E45M17743 | EnoGene | 100 ug | EUR 595 |
PON3 Mouse Monoclonal Antibody [Clone 1F12] |
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E45M17743V-2 | EnoGene | 50 ul | EUR 195 |
PON3 Mouse Monoclonal Antibody [Clone:1B12] |
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E45M17758 | EnoGene | 100 ug | EUR 595 |
PON3 Mouse Monoclonal Antibody [Clone 1B12] |
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E45M17758V-2 | EnoGene | 50 ul | EUR 195 |
PON3 mouse monoclonal antibody,clone OTI1A5 |
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TA807382 | Origene Technologies GmbH | 100 µl | Ask for price |
PON3 mouse monoclonal antibody,clone OTI1A5 |
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TA807382S | Origene Technologies GmbH | 30 µl | Ask for price |
PON3 mouse monoclonal antibody,clone OTI1B12 |
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TA807383 | Origene Technologies GmbH | 100 µl | Ask for price |
PON3 mouse monoclonal antibody,clone OTI1B12 |
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TA807383S | Origene Technologies GmbH | 30 µl | Ask for price |
Mouse Anti-HCMV gH Monoclonal Antibody, clone MAb 5 |
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CABT-NS1153 | Creative Diagnostics | 200 μg | EUR 830 |
Description: Mouse |
PON1 biotinylated detection antibody, ELISA and Luminex validated mouse monoclonal antibody, clone OTI2A6 |
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TA700112 | Origene Technologies GmbH | 50 µg | Ask for price |
PON1 biotinylated detection antibody, ELISA and Luminex validated mouse monoclonal antibody, clone OTI2D4 |
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TA700114 | Origene Technologies GmbH | 50 µg | Ask for price |
Mouse Anti-Ara h1 IgE Monoclonal Antibody (mAb), Clone 2G11G7 |
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7153 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Allergy |
Mouse Anti-Ara h1 IgM Monoclonal Antibody (mAb), Clone 3A1E11 |
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7154 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Allergy |
Mouse Monoclonal Anti-Mouse CD160 mAb, PE, (clone CNX46-3), (mouse IgG2bk) |
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MCD160-PE | Alpha Diagnostics | 50 tests | EUR 416.4 |
CD20 (MS4A1) mouse monoclonal antibody, clone mAb 75 |
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DDX0110P-100 | Origene Technologies GmbH | 100 µg | Ask for price |
KIR2DL4 mouse monoclonal antibody, clone mAb#33, PE |
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AM26033RP-N | Origene Technologies GmbH | 100 Tests | Ask for price |
Mouse Monoclonal Anti-Mouse CD160 mAb, FITC, (clone CNX46-3), (mouse IgG2bk) |
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MCD160-F | Alpha Diagnostics | 50 Tests | EUR 489.6 |
KIR2DL4 mouse monoclonal antibody, clone mAb#33, APC |
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AM26033AC-N | Origene Technologies GmbH | 100 Tests | Ask for price |
PON3 mouse monoclonal antibody, clone OTI4H9 (formerly 4H9) |
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TA807380 | Origene Technologies GmbH | 100 µl | Ask for price |
PON3 mouse monoclonal antibody, clone OTI4H9 (formerly 4H9) |
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TA807380S | Origene Technologies GmbH | 30 µl | Ask for price |
PON3 mouse monoclonal antibody, clone OTI5C3 (formerly 5C3) |
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TA807381 | Origene Technologies GmbH | 100 µl | Ask for price |
PON3 mouse monoclonal antibody, clone OTI5C3 (formerly 5C3) |
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TA807381S | Origene Technologies GmbH | 30 µl | Ask for price |
PON3 mouse monoclonal antibody, clone OTI5B5 (formerly 5B5) |
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TA807428 | Origene Technologies GmbH | 100 µl | Ask for price |
PON3 mouse monoclonal antibody, clone OTI5B5 (formerly 5B5) |
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TA807428S | Origene Technologies GmbH | 30 µl | Ask for price |
Mouse Monoclonal Anti-Mouse CD160 mAb, Biotin, (clone CNX46-3), (mouse IgG2bk) |
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MCD160-B | Alpha Diagnostics | 100 tests | EUR 562.8 |
PON3 mouse monoclonal antibody, clone OTI1F12 (formerly 1F12) |
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TA807353 | Origene Technologies GmbH | 100 µl | Ask for price |
PON3 mouse monoclonal antibody, clone OTI1F12 (formerly 1F12) |
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TA807353S | Origene Technologies GmbH | 30 µl | Ask for price |
Mouse Monoclonal Anti-Mouse CD160 mAb, Purified, (clone CNX46-3), (mouse IgG2bk) |
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MCD160-M | Alpha Diagnostics | 100 ug | EUR 578.4 |
PON1 monoclonal antibody |
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MB11440 | Bioworld Biotech | 50ul | EUR 258 |
Description: Rabbit |
Mouse Anti Mouse BDNF Monoclonal Clone |
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IMSAMLBDNFC120UL | Innovative research | each | EUR 341 |
Description: Mouse Anti Mouse BDNF Monoclonal Clone |
Mouse Anti Mouse BDNF Monoclonal Clone |
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MBS8421710-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Mouse Anti-Mouse Myeloperoxidase (MPO) IgM Monoclonal Antibody (mAb), Clone 8B3A6 |
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7160 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Inflammation |
Mouse Anti-Mouse Myeloperoxidase (MPO) IgG3 Monoclonal Antibody (mAb), Clone 3B6A10 |
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7159 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Inflammation |
KIR2DL4 mouse monoclonal antibody, clone mAb#33, Aff - Purified |
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AM26033PU-N | Origene Technologies GmbH | 100 µg | Ask for price |
Ferritin mouse monoclonal antibody, clone mAb 44, Aff - Purified |
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AM26062PU-N | Origene Technologies GmbH | 200 µg | Ask for price |
Rabbit Anti-Human PON1 Monoclonal Antibody |
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CABT-36017RH | Creative Diagnostics | 100ug | EUR 1008 |
Mouse Anti Mouse TH Monoclonal Clone 5B7D10 |
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IMSAMLTH5B7D10C120UL | Innovative research | each | EUR 282 |
Description: Mouse Anti Mouse TH Monoclonal Clone 5B7D10 |
Mouse Anti Mouse TH Monoclonal Clone 5B7D10 |
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MBS8421747-INQUIRE | MyBiosource | INQUIRE | Ask for price |
ELISA andLuminex validated biotinylated detection antibody PON1 ELISA and Luminex validated mouse monoclonal antibody, clone OTI1F7 |
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TA700113 | Origene Technologies GmbH | 50 µg | Ask for price |
Mouse Anti Mouse GFAP Monoclonal Clone 3H1 |
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IMSAMLGFAP3H1C120UL | Innovative research | each | EUR 260 |
Description: Mouse Anti Mouse GFAP Monoclonal Clone 3H1 |
Mouse Anti Mouse GFAP Monoclonal Clone 3H1 |
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MBS8421725-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Mouse Anti Mouse tPA Monoclonal Clone H27B6 |
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IMSAMSTPAH27B6C1MG | Innovative research | each | EUR 595 |
Description: Mouse Anti Mouse tPA Monoclonal Clone H27B6 |
Mouse monoclonal Anti-MOZ Clone 127A |
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TA353278L | Origene Technologies GmbH | 500 µg | Ask for price |
Monoclonal Functional BAFF-R (mouse) Antibody, mAb , Clone: 9B9 |
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APR16043G | Leading Biology | 0.1mg | EUR 633.6 |
Description: A Monoclonal antibody against Human Functional BAFF-R (mouse), mAb . The antibodies are raised in Purified From Concentrated Hybridoma Tissue Culture Supernatant. and are from clone 9B9. This antibody is applicable in FC |
Mouse Anti Mouse AIF1 Monoclonal Clone 5G4E7 |
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IMSAMLAIF15G4E7C120UL | Innovative research | each | EUR 282 |
Description: Mouse Anti Mouse AIF1 Monoclonal Clone 5G4E7 |
Mouse Anti Mouse AIF1 Monoclonal Clone 5G4E7 |
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MBS8421709-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Mouse monoclonal Anti-BCL10 Clone 151 |
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TA352997L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CDX1 Clone 123a |
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TA353093L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse Anti-D. pteronyssinus Der p2 IgM Monoclonal Antibody (mAb), Clone 2D2B12 |
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7157 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Allergy |
Mouse Anti-D. pteronyssinus Der p1 IgG3 Monoclonal Antibody (mAb), Clone 3H4E1 |
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7158 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Allergy |
Mouse Anti Mouse GFAP Monoclonal Clone 2B12F1 |
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IMSAMLGFAP2B12F1C120UL | Innovative research | each | EUR 282 |
Description: Mouse Anti Mouse GFAP Monoclonal Clone 2B12F1 |
Mouse Anti Mouse PPARG Monoclonal Clone 6D7B9 |
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IMSAMLPPARG6D7B9C120UL | Innovative research | each | EUR 248 |
Description: Mouse Anti Mouse PPARG Monoclonal Clone 6D7B9 |
Mouse Anti Mouse GFAP Monoclonal Clone 2B12F1 |
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MBS8421724-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Mouse Anti Mouse PPARG Monoclonal Clone 6D7B9 |
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MBS8421743-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Anti-PON1 Clone KRJ2 (100 µg) |
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0801014 | Zeptometrix | 100 µg | EUR 292 |
Anti-PON1 Clone KRJ2 (100 ug) |
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801014 | Zeptometrix | 100 µg | EUR 292 |
Mouse Anti-D. pteronyssinus Der p2 IgG2a Monoclonal Antibody (mAb), Clone 3H8D12 |
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7155 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Allergy |
Mouse Anti-D. pteronyssinus Der p2 IgG2b Monoclonal Antibody (mAb), Clone 4C10H3 |
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7156 | Chondrex | 1 mg/ml x 0.1 ml | EUR 246 |
Description: Allergy |
Mouse monoclonal Anti-Mos Clone S3.1 |
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TA353341L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse Anti Human TUBB3 Monoclonal Clone |
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IMSAMLTUBB3C120UL | Innovative research | each | EUR 341 |
Description: Mouse Anti Human TUBB3 Monoclonal Clone |
Mouse Anti Human TUBB3 Monoclonal Clone |
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MBS8421752-INQUIRE | MyBiosource | INQUIRE | Ask for price |
PON1 Rabbit Monoclonal Antibody |
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E10G21865 | EnoGene | 100 μl | EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Mouse monoclonal Anti-EMA Clone E29 |
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TA352816L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CR1 Clone To5 |
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TA353107L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-p63 Clone BU5 |
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TA353532L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-XPA Clone 5A2 |
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TA353547L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-FCGR1 Clone 10.1 |
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TA352787L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-p13 Clone AA10.2 |
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TA352924L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-ANO5 Clone 5F7 |
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TA352973L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD68 Clone KP1 |
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TA353054L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-Cdk1 Clone 3E1.1 |
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TA353088L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-Cdk2 Clone AN4.3 |
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TA353089L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD29 Clone 8E3 |
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TA353270L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-MMP1 Clone 3B6 |
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TA353335L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-MMP2 Clone 4D3 |
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TA353336L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-MMP3 Clone 1B4 |
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TA353337L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-MMP9 Clone 2C3 |
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TA353338L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-MUC1 Clone SM3 |
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TA353346L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-Plx Clone AZ34 |
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TA353386L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-Plx Clone AZ44 |
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TA353387L | Origene Technologies GmbH | 500 µg | Ask for price |
Lipoprotein lipase (LPL) mouse monoclonal antibody, clone Mab-7, Purified |
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BM5512 | Origene Technologies GmbH | 50 µg | Ask for price |
Mouse monoclonal Anti-APC11 Clone AX2.1 |
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TA352969L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-APC4 Clone CIV1.1 |
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TA352971L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD19 Clone BU12 |
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TA353028L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD1c Clone M241 |
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TA353030L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD22 Clone To15 |
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TA353036L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD44 Clone P2A1 |
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TA353042L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD44 Clone BU52 |
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TA353043L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD70 Clone BU69 |
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TA353057L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD72 Clone BU40 |
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TA353059L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CD86 Clone BU63 |
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TA353067L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-Leu2 Clone X107 |
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TA353072L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-Leu2 Clone BU88 |
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TA353073L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-Cdk2 Clone AN21.2 |
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TA353090L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-BORIS Clone 4A7 |
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TA353114L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CYP2C6 Clone K1 |
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TA353125L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-CYP3A1 Clone P6 |
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TA353132L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-NSE Clone NSEP1 |
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TA353161L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-NSE Clone NSEP2 |
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TA353162L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-FGF3 Clone MSD1 |
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TA353194L | Origene Technologies GmbH | 500 µg | Ask for price |
Mouse monoclonal Anti-LewisX Clone 28 |
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TA353199L | Origene Technologies GmbH | 500 µg | Ask for price |